Tract-based Spatial Statistics

Tract-based spatial statistics results in patients with myotonic dystrophy 1 compared with age-matched healthy controls and relationship between the Addenbrooke’s Cognitive Examination–Revised (ACE-R) orientation and attention subscores and mean diffusivity values.

Analyses were adjusted for age. A–C: Voxelwise group differences are shown in blue (mean diffusivity) and red (fractional anisotropy). D) Regions where MD values correlated with the ACE-R orientation and attention subscores are shown in blue. Results are overlaid on the sagittal and axial sections of the Montreal Neurological Institute standard brain in radiological convention (right is left), and displayed at p<0.05 corrected for multiple comparisons. The white matter skeleton is green