Diffusion tensor imaging group comparison at baseline and follow-up. Displayed results of tract-based spatial statistics analyses of different diffusivity indices (FA, AD, RD, MD) are based on a corrected threshold of pfamily wise error < 0.05 and overlaid on the MNI152 Template (resolution 1x1x1 mm) included in FSL. The coordinates refer to the MNI reference space. DTI analyses were performed in 15 DM1 patients and 14 controls. (A) FA reduction in DM1 patients compared with controls at baseline and (B) follow-up. (C) Increase in AD in DM1 patients compared with controls at baseline and (D) follow-up. (E) Increase in RD in DM1 patients compared with controls at baseline and (F) follow-up. (G) Increase of MD in DM1 patients compared with controls at baseline and (H) follow-up.
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