CBF parametric map
Scatter plots of CBF values for controls, patients with MCI, &
patients with AD in both parietal lobes & right medial temporal lobe.
Absolute CBF units are given in ml of blood/100 g of tissue/min. Cont, controls; MCI, mild cognitive impairment; AD, Alzheimer’s disease. Bar shows two standard deviations below and above the mean (horizontal line). p, one-way ANOVA p value. Effect of using different regions to normalize the intensity of CBF parametric maps acquired by MRI on the results of a comparative analysis b/w stable MCI patients, AD patients & healthy controls. Normalization of CBF parametric maps based on whole-brain cortical GM leads to a more sensitive detection of perfusion changes in AD patients than when the cerebellum or whole-brain WM is used.
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