Friday, June 19, 2020

Threshold Free Cluster Enhancement


Clusters of voxels that differ significantly (p<0.05, corrected for multiple comparisons across space (FWE) using 
TFCE (Threshold-Free Cluster Enhancement) between CBS and bvFTD patients for measures of MD
 in blue and FA in red in the axial slices (A and B), and selected coronal and sagittal slices (C and D).

MNI coordinates shown in the axial slices. 

Summary of significant correlations between DTI (either FA or MD) and clinical measures.

Cognitive (MDS-2) and psycho-pathological (NPI) abnormalities were related to focal WM damage in the posterior cingulate bundle, the uncinate fasciculus, and genu of the corpus callosum. (No laterality of findings implied by the depictions of the cerebral hemispheres).

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