Limited functional connectivity is shown to correlate with the MDS-UPDRS part II score. This score positively correlates with the functional connectivity between the pars triangularis and the orbital part of the medial frontal gyrus within the ipsilateral hemisphere, and with the connectivity between ipsilateral inferior parietal lobule and contralateral middle temporal pole.
The MDS-UPDRS part II has a negative correlation with the connectivity between rectal gyrus and the fusiform gyrus in the contralateral hemisphere. (p<0.001) (Blue line: a functional connectivity negatively correlated with the MDS-UPDRS part II score & red line: a functional connectivity positively correlated with the MDS-UPDRS part II score; C: contralateral hemisphere & I: ipsilateral hemisphere).
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