Changes in structural gray matter (GM) volume and functional amplitude of spontaneous low-frequency oscillations (LFO) and functional connectivity density in patients with subcortical vascular mild cognitive impairment (svMCI).
Cortical (A) and subcortical (B) GM volume loss in svMCI
The svMCI patients showed decreased GM volume in several frontal, temporal, occipital and subcortical brain regions. For the details, see Table 2. The statistical threshold was set at P<0.01 for individual voxels and cluster size >948 mm3, which corresponded to a corrected P<0.01 determined by Monte Carlo simulations. Cortical (A) t statistical maps were rendered. Subcortical (B) t statistical map was overlaid on a single anatomical image.
Regions showing GM volume atrophy in the svMCI patients
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