The inferior parietal area in the contralateral hemisphere has substantial functional connectivity positively correlated with the severity of motor symptoms. The contralateral postcentral gyrus also exhibits functional connectivity positively correlated with the severity of motor symptoms. Connectivity between the pars triangularis and the orbital part of the medial frontal gyrus is also positively correlated with the MDS-UPDRS part III score, whereas the connectivity of bilateral rectus gyri is negatively correlated with this score. (p<0.001) (Blue line: a functional connectivity negatively correlated with the MDS-UPDRS part III score & red line: a functional connectivity positively correlated with the MDS-UPDRS part III score; C: contralateral hemisphere & I: ipsilateral hemisphere).
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