Clinical characteristics of all participants (n = 56) in each grade
White matter lesions (WMLs) are frequently observed on Flair and T2-weighted brain MRI scans in clinically normal elderly patients and are strongly associated with increasing age. Chronic ischemia is the underlying cause of WML; therefore, blood flow is decreased not only in white matter lesions but also in areas of NAWM around the lesions and that the reduction of the blood flow in both areas is associated with the severity of WML.
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