Diffusion Tensor Imaging Study of White Matter Damage in Chronic Meningitis

Comparison of fractional anisotropy (FA) between chronic meningitis patients and healthy controls

There was a close relationship between Diffusion Tensor Imaging (DTI) deficits in the limbic system and basal ganglia, and their surrounding CSF space. The correlation between FA decline and CSF space were shown in three-dimensional configuration of the right lateral view (R), antero-posterior view (AP), and left lateral view (L). Gray color, the ventricular system and deep brain arachnoid CSF space; Blue color, parts of the limbic system (cingulate gyrus and para-hippocampal gyrus); Yellow voxels, regions with significantly lower FA value in chronic meningitis vs. normal control (p<0.001, corrected).