The cold colors indicate lower ReHo in HFS group than healthy control group, while the warm colors mean vice versa (p < 0.05, AlphaSim corrected). Color bars represent the t value of the group analysis. Left in the figure indicates the right side of the brain.
Resting-state functional magnetic resonance imaging (fMRI) has been used to detect the alterations of spontaneous neuronal activity in various neurological and neuropsychiatric diseases, but rarely in hemifacial spasm (HFS), a nervous system disorder. HFS is associated with abnormal spontaneous brain activity in brain regions most involved in motor control and blinking movement. The disturbances of spontaneous brain activity reflected by ReHo measurements may provide insights into the neurological pathophysiology of HFS.
The correlation between spasm severity and the ReHo values in brainstem, as well as MFG in the HFS groups.
A. the ReHo value in brainstem is positively correlates with spasm severity in the HFS group (r = 0.404, p = 0.027). B. the ReHo value in MFG is inversely correlates with spasm severity (r = -0.398, p = 0.028). HFS: hemifacial spasm MFG: middle frontal gyrus.
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