WM Integrity in AD

Comparison of the non-apathy group versus the apathy group

Statistical maps corrected for age, education, sex, and TIV showing lower FA values in AD patients with apathy relative to AD patients without apathy. The results were color-coded by p corrected<0.05. Red color denotes regions of declined FA values. AD, Alzheimer’s disease; CDR, Clinical Dementia Rating Scale; FA, Fractional Anisotropy; TIV, Total Intracranial Volume

Correlation between IA scores and FA values

Statistical maps showing the regions of lower FA values correlated with IA scores. The results were color-coded by pcorrected<0.05. FA, Fractional Anisotropy; AD patients with apathy had lower FA values in the genu of the corpus callosum than those without apathy