Lines indicate the edge, and spheres represent nodes. The size of the nodes is proportional to the betweenness centrality (BC). Red denotes hub nodes with BC > 2 standard deviation (SD), and green denotes BC > 1 SD. In DM 1 patients, hub nodes with BC > 2 SD were found only in the left fusiform gyrus, and hub nodes with BC > 1 SD were found in the superior and middle frontal gyrus, and superior temporal gyrus. In controls, hub nodes with BC > 2 SD were found in the right insula, putamen, superior temporal gyrus, and left fusiform gyrus, and hub nodes with BC > 1 SD were found in the middle and inferior gyrus, orbitofrontal gyrus, lingual gyrus, and rolandic operculum.
Results of network metrics and the p-values of AUC comparisons between DM1 and controls.No significant differences were found for measures of global and local network organization (characteristic path length, clustering, efficiency, small-worldness, assortativity, transitivity, and modularity) between DM1 patients and controls.
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