Investigating Structural Brain Changes of Dehydration

Segmented clusters of the gray matter with significant spread during hyperhydration compared to 

dehydration in caudate nucleus and cerebellar regions (indicated by the color code) obtained with VBM.

The upper row shows the results as grayscale Maximum Intensity Projection onto the standard 

SPM glass brain in coronal, axial and sagittal view.

Dehydration can affect the volume of brain structures, which might imply a confound in volumetric and morphometric studies of normal or diseased brain.

Segmented clusters of the white matter with significant spread during hyperhydration 

compared to dehydration in parietal and tempo-parietal regions (indicated by the color code) 

obtained using VBM.

The upper row shows the results as grayscale Maximum Intensity Projection onto the std. 

SPM glass brain in coronal, axial and sagittal view. 

Segmented clusters of the cerebrospinal fluid system with significant distribution during dehydration compared to hyperhydration in the third, fourth, and both lateral ventricles 

(indicated by the color code) obtained with VBM.

The upper row shows the results as grayscale Maximum Intensity Projection onto 

the standard SPM glass brain in coronal, axial and sagittal view.  

Blue color shows effects due to dehydration in regions of the third, fourth, and right lateral ventricle computed with SIENAr (voxel level, uncorrected).

Additionally, effects in the region of the occipital cortex were detected. Clear changes were detected.