Monday, June 29, 2020

Stereotactic Biopsies Using an Intraoperative MR-scanner for Brain Lesions

Location of biopsy targets.



Procedure duration stratified by imaging modality.

The duration of the procedures (time spent in the stereotactic frame) was significantly influenced by the imaging modality used to acquire the stereotactic dataset (One-way ANOVA, p < .000). Post-hoc testing (LSD-Bonferroni) showed significant differences between each individual imaging modality with exception of the CT/MRI pair. Procedures performed with intraoperative CT (iCT) required the least amount of time (median 110 min) followed by iMRI-based biopsies in second place (median 120 min). Imaging performed outside the OR (CT and MRI) considerably increased overall procedure time.

Postoperative imaging, hematoma and neurologic status in the control cohort.

Complication rates and diagnostic yield showed no significant differences between both groups. Mortality was 0.6%, 95% CI = [0.12%, 1.74%], in the iMRI and 0.0% [0.00%, 3.62%], in the control group with a morbidity of 5.4% [3.6%, 7.8%] and 6.0% [2.2%, 12.6%] and a diagnostic yield of 96.8% [94.9%, 98.2%] and 96.0% [90.1%, 98.9%]. Mean procedure duration was 124 [121, 127] minutes using iMRI and 112 [106, 118] minutes in the control group

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