The Relationship b/w Cerebral Glucose Metabolism & Age

Areas of negative correlation between glucose metabolism and age in the female group.

The significant areas overlaid on a T1-weighted MRI image are displayed with a statistical threshold of  FWE-corrected and an extend threshold of 100 voxels. The number of slices correspond to the z values in Talairach coordinate system which defined form inferior to superior. Clusters 1–3 represent the left medial frontal gyrusright cingulate gyrus, the left inferior frontal gyrus and the right superior temporal gyrus respectively. Color scale denotes  value.   

Scatterplots of glucose metabolism in local maximum of each cluster versus age in the female group.

A quadratic polynomial fitting is used to express the relationship between glucose uptake and age. (a) Left medial frontal gyrus, ; (b) Left inferior frontal gyrus, ;

Areas of negative correlation between glucose metabolism and age in the male group.

The significant areas overlaid on a T1-weighted MRI image are displayed with a statistical threshold of  FWE-corrected and an extend threshold of 100 voxels. The number of slices correspond to the z values in Talairach coordinate system which defined form inferior to superior. Clusters 1–4 represent the left superior temporal gyrus, the right superior temporal gyrus, the medial frontal gyrus, and the caudateleft subcallosal gyrus respectively. Color scale denotes  value

Scatterplots of glucose metabolism in local maximum of each cluster versus age in the male group (negative correlation).

A quadratic polynomial fitting is used to express the relationship between glucose uptake and age. (a) Left superior temporal gyrus, ; (b) Right superior temporal gyrus, ; (c) Left medial frontal gyrus, ; (d) Left caudate, .

 Areas of positive correlation between glucose metabolism and age in the male group.

The significant areas overlaid on a T1-weighted MRI image are displayed with a statistical threshold of  FWE-corrected and an extend threshold of 100 voxels. The number of slices correspond to the z values in Talairach coordinate system which defined form inferior to superior. Clusters 1–5 represent the right lentiform nucleus, the left thalamus, the left paracentral lobule, the right middle frontal gyrus and the right precuneus respectively. Color scale denotes  value.