Does HT influence the onset of HD

Evaluate the contribution of AHT to the AO of HD. HD patients with CAGexp ranging between 40 and 50, with known AHT status (86 hypertensives vs. 544 normotensives) and with AHT onset mAO in HD patients with AHT was manifested on average 7 years later than in normotensives (52.5 vs. 45 years, P<0.0001), suggesting that AHT is associated with the appearance of motor symptoms at a later onset HD patient is more likely to be recorded with a history of AHT.

Variance in mAO for each CAGexp allele (40–44 range) in normotensives and in pre-HD AHT patients

Numbers above the square brackets are the difference in median years between Pre-HD AHT and normotensives for each CAGexp allele.